Sunday, April 25, 2010

Diverticular disease

Almost 80% of patients with diverticula are asymptomatic except for chronic constipation. Of those, the other symptoms, the most common presentation is definitely develop into an intermittent and unpredictable pinching lower abdominal complaints (diverticulitis). Additional features of the presentation depend on which of the two main complications of the diverticulum, that developed the affected individual.

One patient, diverticulitis is growing (see later discussion) may present with fever and with theSigns or symptoms and signs of peritoneal irritation (guarding, tenderness, no bowel sounds). A person who could either open diverticular bleeding bloody stools or stools that are good are in place for occult blood is growing.

Diverticulosis results from an acquired malformation of the colon, where the mucosa and submucosa hernia about the underlying muscularis. This is truly a disease of the modern welfare society existence. A rarity at the turn of the century,These days it afflicts 30% of adults in the U.S. population. The incidence increases with age, starting from about 40 years.

Epidemiological studies suggest, as the consumption could be responsible of highly refined foods and less fiber, thus resulting in increased prevalence of chronic constipation, the increased prevalence of the disease, diverticulitis.

Diverticulosis occur: Most acquired diverticula in the colon, the descending colon and sigma (left side) are> 90% of the participatingCases. Both are structural and functional factors contribute to an improvement of as diverticulosis.

Acquired abnormalities in intestinal wall tissue are believed to become the structural basis of diminished resistance to mucosal and submucosal herniation. The functional disturbance as related to chronic intestinal problems and the improvement of a transmural pressure gradient of colonic lumen to peritoneal space as a result of the strong musclesContraction of the intestinal wall.

This functional disturbance is likely to change in dietary habits, decreased fiber makes propulsion of feces that are difficult to typical transmural pressure more. This increased muscle tension that contributes to the development of diverticular disease can, as the abdominal pain that is uncomplicated diverticulitis symptom of the disease be the cause.

The symptoms can take hours to days, withsudden discharge of flatus or feces. Bowel problems or bloating, and diarrhea are typical findings during such episodes, which compared to the proposal that there is a connection between IBS and the improvement of diverticulosis.

The treatment of the symptoms of diverticular disease is contraindicated with opioids because they collect directly to intraluminal pressure and thus may increase the risk of perforation.

Diverticular bleeding:Diverticula are a source of bleeding in 3-5% of patients with diverticulosis. Branches of the colonic intramural arteries (vasa recta) are closely associated with diverticular sac, probably leading to occasional rupture and bleeding. This may be the most common cause of massive GI bleeding reduced in the elderly. Diverticular bleeding is usually painless and not believed to be associated with a main focus of the inflammation.

Diverticulitis: The most common complication ofDiverticulosis increases as a focus of inflammation in the wall of a diverticulum occurs in response to stimulation by fecal material. The patient developed symptoms, from abdominal pain and fever with a chance of progression with or without perforation, abscess.

The perforations are normally separated, but the potential for subsequent fistula formation and intestinal obstruction is high. About a fifth of all people with diverticular disease develop one of the two most importantComplications diverticular bleeding or diverticulitis, which must be distinguished from cancer, inflammatory bowel disease and ischemic disease of injury resulting from diffuse atherosclerosis.

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