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Clinical research to treat malignant mesothelioma is very active and although no treatment has yet proved entirely successful, there exist a range of treatments available to individuals diagnosed with the disease. There are three types of standard treatments used to treat malignant mesothelioma which include: surgery, radiation therapy, and chemotherapy.
Surgery
Surgery for malignant mesothelioma is divided into a number of sub-classes, which are specially designed to limit the disease for individuals with particular strains of the disease.
Extrapleural pneumonectomy is a severe form of surgery in which the entire lung and a portion of the lining of the chest, the diaphragm, and some or the entire sac which surrounds the heart is removed.
Wide local excision is a form of surgery which targets and removes the cancer and a limited amount of the healthy tissue surrounding the cancerous region.
Pleurectomy and decortication removes part of the covering of the lungs, as well as the lining of the chest and portions of the outside covering of the lungs.
The surgical procedure pleurodesis is a distinct technique insofar as it employs a blend of chemicals and/or drugs to create an intentional scar between the layers of the pleura. Post surgery, the space created by the scar must be drained, using either a catheter or chest tube, and is then filled with a chemical which inhibits the accumulation of fluid in the pleura cavity.
Radiation
The second primary medical technique used to fight the development of malignant mesothelioma is radiation. Radiation therapy, as applied to malignant mesothelioma uses the same basic technology as other forms of medical radiation insofar as the technique employs high energy x-rays to kill cancer cells. The process is divided into two broad categories:
External radiation therapy is a technique in which a machine sends radiation in a targeted stream at a certain portion of the body, and in so doing it kills the cancerous cells in its purview.
Internal radiation therapy, by contrast, uses not an external machine, but rather needles, seeds and catheters to place radioactive substance directly on or near the cancer. While the precise method of implementation will of course depend upon the type and stage of the illness, what is constant within this category is that the goal is to get the radiation placed directly onto the cancerous area and in so doing provide a more concentrated and directed dosage.
Chemotherapy
The third standard malignant mesothelioma treatment is Chemotherapy. Chemotherapy uses drugs which target cancer cells and stop them from dividing and thus prevent their growth.
In systemic chemotherapy, the drug can be taken by mouth or injected, but either way the goal is to have it reach cancer cells by means of the body's own blood circulation system. In regional chemotherapy, the drug is placed directly onto the target area. And finally, combination chemotherapy involves the use of two or more anticancer drugs which can be administered either orally or through injection.
Malignant mesothelioma is a difficult disease for anyone to bear, however, educating oneself as to the options available is an important step for making the process more manageable.
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Mesothelioma is an aggressive cancer that affects the membranes surrounding the internal organs of humans. When not detected until it has progressed to a late stage, it is often difficult, if not impossible to control. Adding to the particular danger of this cancer is that the symptoms are very general and non-specific. Because of this, it is often not diagnosed early enough. Exposure to asbestos is the leading cause of mesothelioma, documented in nearly all cases.
Because of its aggressive spread, you should contact your doctor as soon as you begin to suspect mesothelioma, especially if you have been exposed to asbestos at some point. You can first expect a screening from your doctor, which can include a variety of tests like X-Rays or CT scans. If these preliminary tests show any sign of mesothelioma, you can expect a long series of additional tests to rule out any other diseases.
The only definitive test for mesothelioma is a moderately invasive procedure called a biopsy. If your previous screenings come back positive, a small sample of tissue will be removed from the affected area and examined by a specialist. There are many different types and techniques of biopsy at your doctor's disposal, and he/she will select the right one depending on where the cancerous growth is located. Depending on which stage your cancer has advanced to, your Mesothelioma therapy options may be many. Mesothelioma can be classified as being in one of four stages of development.
Stage I is the earliest and very localized. If found at this stage, the prognosis can be quite good. Therapy options at this point can include surgical removal of the tumor, chemotherapy or radiation therapy. Clinical trials may also be used on a limited basis to determine the usefulness of new cancer fighting compounds.
Stage II refers to mesothelioma that has spread to other areas near the tumor. Once the cancer begins to spread, the prognosis rapidly deteriorates, however with the right treatment and mindset, hope for recovery still remains. Many of the same therapies for stage I are used for Stage II. Quite often with an individual who has stage I or stage II mesothelioma, the doctor will employ several therapies in conjunction with one another. While very effective, this can leave the patient in a very weakened state, and thus is not recommended for more advanced stages.
Stage III indicates the cancer has spread to the lymph nodes. At this point, techniques such as surgery are limited in their effectiveness, simply because of the volume of cancer in the patient. If surgery is elected during stage III or IV, it is usually to increase the quality of life for the patient. Radiation and chemotherapy can still be used at this stage as a mesothelioma therapy, however their ability to control the cancer is diminished significantly.
Stage IV is the most advanced type and is applied to cases where the cancer has spread to parts of the body far removed from the tumor. Usually, when stage IV is reached, the mesothelioma spreads to the brain and the prognosis is very low. Mesothelioma therapy options at this point are usually used to improve the patient's quality of life, although there have been cases where a patient has been responsive enough to treatment that remission is achieved.
The number one asset you have in beating this cancer has little to do with choosing your mesothelioma therapy, but is catching your disease early. More than the different techniques used to combat the cancer, the early discovery of it can determine your prognosis.
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