Mesothelioma is a very aggressive and rare form of cancer, the diagnosis is difficult, and that is also very resistant to treatment. Approximately 2000-3000 new cases of malignant mesothelioma are seen each year in the U.S., and these numbers are expected to increase over ten years the next.
What causes mesothelioma?
There is a large and undeniable evidence that medical mesothelioma caused by exposure to asbestos fibers. There are no other known. Cause
Asbestos is a naturally occurring fibrous material that has been widely used in industry, trade and domestic goods throughout the 20th Century. It was especially popular because of its durability, fire resistant and insulating properties. It was used in thousands of different products manufactured asbestos.
These include building materials, household appliances and pads, was the use of so common that millions of Americans were exposed unknowinglythe toxic material, which now leads to the development of mesothelioma among millions of Americans.
Most companies that these asbestos-contaminated products were manufactured, Aware of the danger of asbestos, but still prefer to bring millions at risk to make big profits.
But today, as more cases are diagnosed and they are looking for statutory compensation is ordered by these companies to pay compensation for patients affected by asbestos.
How doesAsbestos causes mesothelioma?
Internal organs and body cavities are lined by a thin tissue called the mesothelium. This lining of the lungs-lines () and it also lines the pleural pericardium () pericardium and abdominal cavity () peritoneum.
These mesothelial tissue provides protection and support for the internal organs and body cavities. It also provides lubrication organ functions smoothly and in good health.
Mesothelioma concerned is the lining of various organs andBody cavities, especially the pleura, pericardium and peritoneum. Occasionally, and in rare cases of cancer of the lining of the testicles, called the tunica vaginalis.
Although the actual mechanism by which asbestos causes cancer is not known, there are about four different theories to explain this:
1-asbestos causes irritation and inflammation of mesothelial cells, results in irreversible scarring, cell damage and eventually cancer
2 - asbestos fibers enter cellsand disrupt the function of cellular structures that are essential for normal cell division, cause cellular changes that lead to cancer.
3-asbestos causes the production of free radicals. These molecules damage DNA and cause cells to mutate and be vicious.
4 the presence of asbestos causes cells produce oncoproteins. These molecules cause mesothelial cells to ignore normal limits cell division, and this can lead to development of cancer.
The commonPathophysiology in each of these theories is that asbestos causes cellular damage, mainly by sharing the cells of the mesothelium and multiply unchecked leads to the formation of tumors. This uncontrolled division causes impairment in normal functioning of body organs and tissues.
Is mesothelioma have other causes?
and medical knowledge it is not able to prove Although the research, just any other cause of mesotheliomaAsbestos exposure, it is that smoking may worsen to a less serious asbestos diseases like asbestosis, and rapid formation of tumors and the development of cancer known.
Also asbestos exposure and smoking have a synergistic effect that the risk of developing lung cancer by up to 84 times or more. So people who were to asbestos for a longer period are exposed to advise not to smoke.
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