Wednesday, January 26, 2011

Clinical trials for mesothelioma: Who are involved, stages and Mesothelioma Clinical Trial Reports

What is a clinical trial?

A clinical study is carried out a study on humans for a very strict protocol. The goal of a clinical study is to develop new drugs and disease treatments for all types of, especially those fatal as mesothelioma.

Before any drug is considered effective and safe to carry for the general public, it must undergo a thorough process in a clinical study.

Who are involved in mesotheliomaclinical studies?

The people in these biomedical studies involved are researchers from which are the very detailed plan on how the process is carried out, the volunteers, the subject of the hearing will be and the review board consisting of the rule of scientists, oncologists, other doctors and nurses.

The Review Board is indirectly related to the procedure, but it monitors the process and gives an annual formal review. The volunteers who participate are, in mostCases, patients diagnosed with mesothelioma and other types of malignant cancers. Most mesothelioma patients use of clinical trials as their last hope of a cure.

What are the stages of a clinical study carried out?

To avoid confusing the term "step" with the seriousness or extent of disease, we use the term "phases".

In general, a clinical study, three phases, with a fourth phase is now being considered for the purposes ofPost-marketing studies. The fourth phase is essentially to review the effectiveness of FDA-approved drug that had already gone through all three phases.

The first phase determines the correct drug dosage, and focuses mainly on safety rather than efficacy of the drug. The test is done on a small group of 20-80 people for the first phase.

The second phase checks whether the new drug has a specific effect against a certain disease. This is also the ideal dosage of the drugevaluated and the results of the first phase is confirmed. The test is based on a larger group of people carried out to 100-300 people.

The third phase compares the new drug against the existing standard treatment for a disease or illness. The new drug is combined with other drugs to determine side effects and different doses are tested for the same purpose and to verify the effectiveness of the drug. The last stage is performed on a large scale, in which up to 3,000 peoplethe participants.

Do all mesothelioma patients have clinical exams this?

Mesothelioma patients are under no obligation to participate in biomedical studies and researches. Oncologists may recommend this, especially when patients taking into account new types of treatment, but the decision lies with the patient and the patient's family.

Trial reports of mesothelioma cases raise hope for mesothelioma patients. TheReport summarizes the results of the research method and is normally published in medical journals for review and as a basis for further experiments with other health professionals to serve.

There are various types of mesothelioma, would be a single clinical trial is successful enough for all types of this disease?

There were reports of Mesothelioma Mesothelioma Clinical Trial conducted for different types and scale. A fewExamples include the following:

For advanced malignant pleural mesothelioma (developed in the lining of the lungs), Phase III Vorinostat study was conducted in which vorinostat with a chemotherapy drug called doctors to kill cells into cancer cells and stop cell division by blocking enzymes, cells, cancer cells are required for to multiply.

For advanced malignant mesothelioma, II pemetrexed disodium with gemcitabine phase of a study conducted to investigate the effects ofChemotherapeutic agents such as gemcitabine and pemetrexed disodium in recurrent malignant mesothelioma.

For patients with inoperable malignant mesothelioma, AZD2171 II clinical trial was conducted, so that doctors can examine live enzymes inhibit the use of such chemotherapeutic agents for block and blood flow in the tumor. The study was dedicated to help patients with advanced mesothelioma, sarcotamous, and recurrent malignant epithelial cells.

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